21 Net

The Company was formed in 2001 to develop a system to connect high speed trains to the internet. Using advanced technology, customers on high speed trains travelling at up to 300 kilometres an hour can access information from websites or send and collect urgent emails from their laptop computers and PDAs. The Company secured its first major contract in 2007 to install its system onto 26 trains for Thalys.

Aeristech Limited

Aeristech has developed a novel fuel efficient and low-cost hybrid turbocharger technology with applications in the automotive and power generation industries. The traditional turbocharger is decoupled into a turbine and a compressor powered by an electric motor. The electrical storage created provides an opportunity to vastly reduce turbo lag resulting in increased performance and reduced emissions. This enables automotive manufacturers to downsize engines without impacting performance.

Aitua

Allinea Software

Anaxsys Technology

Anaxsys Technology, which is based at Keele University in Staffordshire, is a medical technology company developing a suite of devices which allow the diagnosis and monitoring of a variety of respiratory diseases by analysing the humidity profile of human breath. With long term potential to screen for lung cancer and monitoring the treatment of asthma, its first product will be a respiratory rate monitor for use in the care of patients recovering from operations.

Ardentia

BHMG Marketing

Cellcentric

Chameleon Biosurfaces

Chameleon Biosurfaces is developing the next generation of polymer coatings for implantable medical devices, such as drug eluting stents.  The polymers provide beneficial features that enhance implants performance.  Beneficial features can include minimising adverse events that can occur in patients after devices have been implanted, and features that help clinicians in the successful deployment of implants during operations.

Claresys Limited

Clearview Systems Limited

Clearview is a leading provider of performance management software for the housing association sector.  The software was originally developed in house by Festival House Group, realising the  commercial potential use of the system to other housing associations the software was span out into a joint venture in 2003.  Clearview has a suite of modules that assist housing associations with strategic business planning, performance management and customer service improvement.  Clearview now has over 90 registered social landlords using the clearview software managing over half a million homes.

Colbalt Light Systems

Cobalt Light Systems provides new and proprietary analysis techniques using Raman spectroscopy for high throughput non-invasive pharmaceutical analysis of tablets, capsules, powders etc. incuding chemical and polymorph/amorphous content.  A second technique involves the rapid non-invasive analysis of materials below layers e.g. materials characterisation through coloured and opaque containers for pharmaceuticals/security uses, tissue analysis through skin and academic research.

Comply Serve

Concurrent Thinking

Crescendo Biologics

Crescendo Biologics is developing two proprietary platforms for biological therapeutics from the Babraham Institute: ribosome display for the optimization of antibodies and a transgenic mouse which produces heavy chain only antibodies.

Cytox

Cytox is developing a diagnostic test and therapeutic cures for Alzheimer's Disease which is estimated to affect 15 million people worldwide. The company is a university spin-out based on groundbreaking academic research into the role of the cell cycle in neuro-degenerative diseases.

Dynamic Change

Dynamic Change was formed in March 2000 to develop a web-based performance management software tool. Performance Accelerator is an online integrated corporate governance solution that allows organisations to manage and monitor their business objectives, risks, performance indicators, compliance reporting, financial targets and regulatory obligations. Dynamic Change is the market leader in its chosen market; the NHS. The Company was originally backed by an investment from the HSBC fund in 2002 with a follow-on investment by the Advantage Growth Fund in August 2003.

Everyclick Ltd

Gemba Solutions

Gemba Solutions develops real time performance management software. The company has three offerings, Lean Impact, OEE IMPACT Manual Entry and OEE IMPACT Connect. Lean Impact comprises a suite of software modules, each of which is a productivity tool in its own right and when combined, provide the user with a comprehensive manufacturing execution system. Manual Entry and Connect are based on a subset of the full Lean Impact suite, enabling the user to move up to a fully automated system as required.

Inscentinel

Inscentinel Ltd is a biotechnology company specialising in harnessing the olfactory ability of insects for trace vapour detection. Our primary focus is the development of a new generation of handheld portable detectors, through the use of live honeybees. This unique Inscentinel Technology offers sensitive vapour detection coupled with distinct operational advantages.

Ionic Polymer Solutions

IPS is a spin out from Novel Polymer Solutions Limited (NPS), an existing Advantage Growth Fund investment. NPS has granted to IPS the exclusive right to exploit the intellectual property in the manufacture of proton conducting monomers and polymers using novel UV curable diene systems. The technology has a number of potential applications including water free proton conduction in fuel cells and anion pumping for acid regeneration in the metal finishing processes.

i-Solutions Global

i-Solutions has developed i-nexus a suite of performance improvement and strategy exaction software. The Company has a US sales office and a truly global blue-chip customer base. Following an initial investment from the Advantage Growth Fund significant further investment has been raised by the company from Herald Venture and Antrak Capital to fund its continued growth development.

L3 Technology

Lontra Limited

Lontra is an innovative clean tech business, which is developing a proprietary energy efficient compressor and engine design with applications including waste water treatment, industrial air and automotive superchargers.

LumeJet Ltd

LumeJet Ltd is a leading light in the world of photonic imaging and is revolutionising the industry. It has developed ground breaking platform technologies - 'LumeJet®Imaging System' and 'LumeJet®Imaging Engine. These bring to the industry lower costs, an easy way to integrate and operate, across a wide and growing range of applications where light is used to activate. The LumePress™is a range of ultra high quality printers that utilises LumeJet's innovative technology - the LumeJet™Imaging Engine. The LumePress™printer range delivers significant cost and quality advantages especially where documents are image intensive or where output quality is key. LumeJet's revolutionary technology can be used in many applications, including third party integration of the core technology for use across a number of industries including - printing, packaging, plastic logic, polymer imaging, digital pre-press, and pcb marking.

Microbial Solutions

Microbial Solutions’ innovative on-site bacterial process can treat metal working fluids in a much more environmentally friendly manner, producing grey water that is safe to dispose of in the sewerage system, and with no methane production in the process - so lower greenhouse gas impact. Water re-use is also possible, and the Company can offer treatment price certainty and stability to manufacturers, on a non-capital investment ‘pay-as-you-treat’ per litre basis.

The technology has been successfully trialed with a leading car manufacturer. Microbial Solutions has now moved to new office and laboratory facilities in Oxfordshire, and following an introduction by Houghton Europe, is also close to completing the first commercial pilot of its patent protected bacterial treatment, known as ‘Microcycle™ Technology’ at the site of a major aerospace manufacturer. RSF made a pathfinder investment in 2004 and the Company raised £1.2m towards the end of 2007 from a syndicate including RSF and Oxford Capital Partners.

Microvisk

Microvisk has a unique approach to the measurement of the viscosity of blood and other fluid, based on CCLRC's considerable expertise in its Central Microfabrication Facility. The patented technology involves the spatial movement of microfabricated thermal bimorohs - bimetallic strips - which is converted into an electric signal using the piezo electric effect. Microvisk's technology can revolutionise the diagnostic market by simplifying the most common coagulation tests (those that are critical to the monitoring of any patient at risk from blood clotting and heart problems) and by providing instant POC and NP testing and analysis.

Midland Industrial Glass

Midland Industrial Glass is a precision engineer manufacturing glass components for television stands, shop fitting and leisure equipment as well as for a wide range of other applications. It uses state of the art CNC technology for shape cutting, edging, drilling, bevelling, printing and toughening its products. It specialises in short runs, quick turnrounds and technically difficult products in long runs to set it apart from its competitors.

MVI Holdings

Novacta

Novel Polymer Solutions

Novel Polymer Solutions was formed to exploit a new system of producing radiation curable polymers developed by Qinetiq in their Malvern research centre. This introduces the scope to produce polymers with properties that are novel or otherwise difficult to achieve. The method allows the simple production of mimics of conventional polymers and the creation of new and novel polymers via a radiation curable monomer. Other investors include the Environmental Technologies Fund who invested £3.5m in 2008.

Occam Systems

Occam Systems Limited is the major supplier in the UK of software for managing student accommodation and events for universities. With a dominant position in the market, Occams' software handles everything from receiving students' applications for accommodation, issuing contracts and managing rooms, through to collecting rent and debt management. The software has grown to manage events, meeting rooms, catering and audio visual services.

Orbital Optics

For several years CCLRC's Space Science and Technology Department at Rutherford Appleton Laboratory has been developing compact, robust, low cost cameras to image Earth from space. The TopSat mission, a collaboration with Surrey Satellites and Technology Ltd and QinetiQ on a BNSC and MoD sponsored project, obtained colour images at a resolution of 2.8m over a 16km field of view. Individual buildings on the ground can be identified at this resolution.

MDA,the Canadian space and defense company, acquired 50% of the conmpany's share capital in 2007 (including the bulk of RSF's holding) with a view to developing it as its European base.  Rainbow made and IRR of 20% in less than 1 year.

Oxsensis

Oxsensis is pioneering a 'new breed' of optical instrumentation for precision controls in super harsh environments such as highly efficient car and aero engines, and in industrial,electrical,nuclear and space applications.

P2i

P2i's patented technology employs a special pulsed ionised gas (plasma), which is created within a vacuum chamber, to attach a nanometre-thin polymer layer over the entire surface of a product.  Tests show that P2i's patented nano coating technology can deliver performance benefits for a wide range of materials, including polymers, metals, fabrics, leather, ceramics, glass and paper.  Even complex, 3D objects incorporating several different materials can be treated successfully with the P2i process.  P2i has two consumer brands for its technology: ion mask™, for footwear, outdoor clothing and accessories, and Aridion™, for consumer electronics.  For industrial applications, the technology is covered by the corporate P2i brand.

Phasor Solutions

pr2go

pr2go enable businesses of all types and sizes to gain valuable press coverage at an affordable price whenever they need it.  In 24 hours pr2go will guarantee to write professional press releases and then distribute them to all the relevant media required by the customer.  They supply a cost effective online virtual marketing agency.  They will deliver this discipline at a fraction of the cost of traditional PR agencies. pr2go intend to replicate the proposition concentrating on other key marketing services such as creative design and new media.

Procarta Biosystems

ProKyma

Prolojik

Quantum Risk Management

Quantum Risk Management provides tailored, cost effective solutions to risk management problems. They aim to help their clients achieve sustained improvement by providing services ranging from risk assessments, through corporate auditing, to health and safety management systems.

SALT

Subsea Asset Location Technologies Ltd (SALT) is a spin-out company from the Defence Science and Technology Laboratory (Dstl), a research agency of the UK Ministry of Defence (MOD).  The company was formed to exploit a new passive sonar reflector technology for the commercial marketplace.  The product SonarBell™ works by focusing the sound energy like a lens to amplify sound levels and reflect them to the sender.  This ability is delivered solely through the mechanical properties of the chosen materials and its construction.

ScriptSwitch

ScriptSwitch is the market leading provider of an innovative prescribing software product to NHS Primary Care Trusts, which is then employed by GPs in their surgeries. The software is a sophisticated medicines management tool that delivers consistency and conformity in prescribing whilst quantifying and reporting on cost savings. The product has enabled PCT's to save millions of pounds from their drug budgets. The Advantage Growth Fund backed Scriptswitch as a start-up business and achieved a partial exit in 2007, following a significant investment of development capital by Isis Equity Partners, generating an IRR to date for the fund of 67%.

Silver Lining Solutions

Silver Lining Solutions, formed in 1999, is an online skills assessment specialist. It develops software for training needs analysis, compliance testing, and knowledge assessment. Sales are to both public and private sector and a significant sale to the O2 call centre has opened the call centre market to the Company. Its product 'Discover' automates the processes for testing operatives' skills and embedding the results into switching software. The result for the call centre is that callers are put through to the operative best able to deal with their query.

Simworx

Speed Plastics

Streamline Computing

T@lecom

WalkinWifi Limited

WalkinWiFi™ provides totally free of charge Wi-Fi internet access to members of the public, across a national network, in return for their agreement to be marketed to, via e-mail and text message, by the location at which they first register for use of the system. WalkinWiFi™ then provides a web based marketing message delivery suite for the location to be able to simply and cost effectively send out offers and updates to encourage customers to return to site.

Warwick Effect Polymers

Warwick Effect Polymers has developed a new technology, transition metal mediated Living Radical Polymerisation, which allows the production of complex polymers under greater control than conventional polymerisation techniques. The company is looking to exploit its platform technology to become a provider of polymer technology to the pharmaceutical and healthcare industries.